Bacteria Contaminant Interactions
Ronald W. Harvey
U.S. Geological Survey, National Research Program

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visits since Aug, 1997.

Last Update 06/06/11


Project Bibliography                                 Recent Papers


  1. Harvey, R.W., Smith, R.L., and George, L., 1984, Effect of organic contamination upon microbial distributions and heterotrophic uptake in a Cape Cod, Mass. aquifer. Appl. Environ. Microbiol., Vol. 48, p. 1197-1202.  PDF file

  2. Harvey, R.W., and George, L.H., 1987, Growth determinations for unattached bacteria in a contaminated aquifer. Appl. Environ. Microbiol., Vol. 53, p. 2992-2996.  PDF file

  3. Harvey, R.W., 1989, Considerations for modeling transport of bacteria in contaminated aquifers. In Abriola, L., ed., Groundwater Contamination: Oxfordshire, UK, IAHS Press, No. 185, p. 75-82.
  4. Harvey, R.W., George, L.H., Smith, R.L., LeBlanc, D.R., 1989, Transport of microspheres and indigenous bacteria through a sandy aquifer: Results of natural and forced-gradient tracer experiments. Environ. Sci. Technol., Vol. 23, p. 51-56.  PDF file

  5. Kuwabara, J.S., and Harvey, R.W., 1990, Application of a hollow-fiber tangential-flow device for sampling suspended bacteria and particles from natural waters. J. Environ. Qual., Vol. 19, p. 625-629.
  6. Harvey, R.W., 1991, Parameters involved in modeling movement of bacteria in groundwater. In Hurst, C.J., ed., Modeling the Environmental Fate of Microorganisms: Washington, American Society for Microbiology, p. 89-114.
  7. Harvey, R.W., and Garabedian, S., 1991, Use of colloid filtration theory in modeling movement of bacteria through a contaminated sandy aquifer. Environ. Sci. Technol., Vol. 25, p. 178-185.  [PDF file]

  8. Smith, R.L., Harvey, R.W., and LeBlanc, D.R., 1991, Importance of closely spaced vertical sampling in delineating chemical and microbiological gradients in groundwater studies. J. Contam. Hydrol., Vol. 7, p. 285-300. PDF file
  9. Bitton, G. and Harvey, R.W., 1992, Transport of pathogens through soil. In Mitchell, R., ed., Environmental Microbiology: New York, Wiley-Liss, pp. 103-124.  PDF File
  10. Harvey, R.W. and Bouwer, E.J., 1992, Limits on quantitative descriptions of biocolloid mobility in contaminated groundwater. In McCarthy, J.F. and Wobber, F.J., eds., Concepts in Manipulating Groundwater Colloids for Environmental Restoration. London, Lewis Publishers, pp. 57-64.
  11. Harvey, R.W. and Garabedian, S., 1992, Response to comment on "Use of colloid filtration theory in modeling movement of bacteria through a contaminated sandy aquifer". Environ. Sci. Technol., Vol. 26, p.401-402.
  12. Harvey, R.W. and Widdowson, M., 1992, Microbial distributions, activities, and movement in the terrestrial subsurface: experimental and theoretical studies, in Wagenet, R.J., Baveye, P., and Stewart, B.A., eds., Interacting Processes in Soil Science: London, Lewis Publishers, pp. 185-225.
  13. Harvey, R.W. and Barber, L.B., 1992, Associations of free-living bacteria and dissolved organic compounds in a plume of contaminated groundwater. J. Contam. Hydrol., Vol. 9, p. 91-103.  PDF file

  14. Scholl, M.A. and Harvey, R.W., 1992, Laboratory investigations on the role of sediment surface and groundwater chemistry in transport of bacteria through a contaminated sandy aquifer. Environ. Sci. Technol., Vol. 26, p. 1410-1417.   [PDF doc]

  15. Harvey, R.W., Kinner, N.E., MacDonald, D., Metge, D.W. and Bunn, A., 1993, Role of physical heterogeneity in the interpretation of small-scale laboratory and field observations of microorganism, microsphere, and bromide transport through aquifer sediments. Water Resour. Res., Vol. 29, p. 2713-2721.   PDF file

  16. Metge. D.W., Brooks, M., Smith, R., and Harvey, R.W., 1993, Effect of treated-sewage contamination upon bacterial energy charge, adenine nucleotides, and DNA in a sandy aquifer on Cape Cod. Appl. Environ. Microbiol., Vol. 59, p. 2304-2310. PDF file

  17. Harvey, R.W., 1993, Fate and transport of bacteria injected into aquifers. Curr. Opin. Biotechnol., Vol. 4, 312-317 [invited summary of the state of the art, J. Tiedje (ed.)].  PDF FIle
  18. Novarino, G., Warren, A., Kinner, N.E., and Harvey, R.W., 1994, Protists from a sewage-contaminated aquifer on Cape Cod, Massachusetts, U.S.A. Geomicrobiol. J., Vol. 12, p. 23-36.
  19. Bales, R.C., Li, S., Maguire, K.M., Yahya, M.T., Gerba, C.P., and Harvey, R.W., 1995, Virus and bacteria transport in a sandy aquifer, Cape Cod, MA. Ground Water, Vol. 33, p. 653-651.   PDF file
  20. Barber, L.B., Krueger, C., Metge, D.W., Harvey, R.W., and Field, J.A., 1995, Fate of linear alkylbenzene sulfonate in groundwater: implications for in situ surfactant-enhanced remediation, in Sabatini, D.A., Knox, R.C., and Harwell, J.H., eds., Surfactant-Enhanced Subsurface Remediation: Washington, American Chemical Society, pp. 95-111.
  21. Harvey, R.W., Kinner, N.E., Bunn, A., MacDonald, D., and Metge, D., 1995, Transport behavior of groundwater protozoa and protozoa-sized microspheres in sandy aquifer sediments. Appl. Environ. Microbiol., Vol. 61, 209-217.  PDF file

  22. Loveland, J.P., Ryan, J.N., Amy, G.L., and Harvey, R.W., 1996, The reversibility of virus attachment to mineral surfaces. Colloid Surfaces. A: Physicochem. Eng. Aspects, 107:205-221.  PDF file

  23. Harvey, R.W., 1997, In situ and laboratory methods to study subsurface microbial transport. In Hurst, C.J., Knudsen, G.R., McInerney, M.J., Stetzenback, L.D., and Walter, M.V., eds., Manual of Environmental Microbiology: Washington, ASM Press, p. 586-599.  PDF file
  24. Harvey, R.W., Suflita, J.M., and McInerney, M.J., 1997, Overview of issues in subsurface and landfill microbiology. In Hurst, C.J., Knudsen, G.R., McInerney, M.J., Stetzenback, L.D., and Walter, M.V., eds., Manual of Environmental Microbiology: Washington, ASM Press, p. 523-525.
  25. Harvey, R.W., Metge, D.W., Kinner, N., and Mayberry, N., 1997, Physiological considerations in applying laboratory-determined buoyant densities to predictions of bacterial and protozoan transport in groundwater: Results of in-situ and laboratory tests. Environ. Sci. Technol., 31:289-295.   PDF file

  26. Pieper, A.P., Ryan, J.N., Harvey, R.W., Amy, G.L., Illangasekare, T.H., and Metge, D.W., 1997, Transport and recovery of bacteriophage PRD1 in a sand and gravel aquifer: Effect of sewage-derived organic matter. Environ. Sci. Technol. 31:1163-1170. PDF file

  27. Harvey, R.W., 1997 Microorganisms as tracers in groundwater injection and recovery experiments: A review. FEMS Microbiol. Rev.  20:249-259. PDF file
  28. Novarino, G., Warren, A., Butler, H., Lambourne, G., Boxshall, A., Bateman, J., Kinner, N.E., Harvey, R.W., Mosse, R.A., and Teltsch, B., 1997, Protistan communities in aquifers: a review. FEMS Microbiol. Rev. 20:261-275.   PDF file
  29. Kinner, N.E., Harvey, R.W., and Kazmierkiewicz-Tabaka, M., 1997, Effect of flagellates on free-living bacterial abundance in an organically-contaminated aquifer. FEMS Microbiol. Rev. 20:249-259.  PDF file

  30. N. E. Kinner, R. W. Harvey, K. Blakeslee, G. Novarino, and L. D. Meeker,  1998, Size-Selective Predation on Groundwater Bacteria by Nanoflagellates in an Organic-Contaminated Aquifer, Appl. Envir. Microbiol.,  64: 618-625. PDF file

  31. Krueger, C. J., Barber, L. B., Metge, D. W., Field, J. A.,  1998,  Fate and Transport of Linear Alkylbenzenesulfonate in a Sewage-Contaminated Aquifer: A Comparison of Natural-Gradient Pulsed Tracer Tests, Environmental Science & Technology; 32(8); 1134-1142. PDF file

  32. Ryan, J. N., Elimelech, M., Ard, R. A., Harvey, R. W., Johnson, P. R., 1999.  Bacteriophage PRD1 and Silica Colloid Transport and Recovery in an Iron  Oxide-Coated Sand Aquifer, Environmental Science & Technology; 1999; 33(1); 63-73.  PDF file

  33. Campbell Rehmann, L.L., Welty, C., and Harvey, R.W., 1999, Stochastic analysis of virus transport in aquifers. Water Resour. Res., Vol. 35,  1987-2006.  PDF file

  34. Campbell Rehmann, L.L., Welty, C., and Harvey, R.W., 2000, Reply to Comment on "Stochastic analysis of virus transport in aquifers". Water Resources Res., Vol. 36: 1983-1984.  PDF file

  35. Harvey, R.W. and Harms H., 2001, Transport of Microorganisms in the Terrestrial Subsurface: In Situ and Laboratory Methods, Chapter 69, In Hurst, C.J., Knudsen, G.R., McInerney, M.J., Stetzenback, L.D., Crawford, R.L., eds., Manual of Environmental Microbiology, 2nd Edition: Washington, ASM Press, p. 753-776   PDF file

  36. Harvey, RW and Harms, H., 2001, Tracers in Groundwater: Use of Microorganisms and Microspheres. In G. Bitton et al., eds., Encyclopedia of Environmental Microbiology, 6: 3194-3202. John Wiley & Sons, Inc., New York, 2002. PDF file

  37. Harvey, R.W., Suflita, J.M., and McInerney, M.J., 2001, Overview of issues in subsurface and landfill microbiology., Chapter 63., In Hurst, C.J., Knudsen, G.R., McInerney, M.J., Stetzenback, L.D., Crawford, R.L., eds., Manual of Environmental Microbiology, 2nd Edition: Washington, ASM Press, p. 675-695. PDF file

  38. Harvey, RW, Mayberry, N., Kinner, NE, Metge, DW and Novarino, F 2002, Effect of Growth Conditions and Staining Procedure upon the Subsurface Transport and Attachment Behaviors of a Groundwater Protist,  Appl. Env. Microbiol.,  68: 1872-1881.  PDF file
  39. Kinner , N E; Harvey, R. W.; Shay, D. M.; Metge, D. W.; Warren, A.;  2002, Field Evidence for a Protistan Role in an Organically-Contaminated Aquifer; Environ. Sci. Technol., 36,4312-4318. PDF file
  40. Ryan, JN, Harvey, RW,   Metge, DW, Elimelech, M,  Navigato, T, and Pieper, AP  2002  Field and Laboratory Investigations of Inactivation of Viruses (PRD1 and MS2) Attached to Iron Oxide-Coated Quartz Sand  Environmental Science & Technology; 2002; 36(11); 2403-2413PDF file
  41. Harvey, RW, and Harms, H. 2002.  Tracers in Groundwater: Use of microorganisms and microspheres.  in Ref: In G. Bitton et al., ed., Encyclopedia of Environmental Microbiology, 6: 3194-3202. John Wiley & Sons, Inc., New York, 2002.
  42. Van Cuyk, S,  RL Siegrist, K Lowe and RW Harvey  2004. Evaluating Microbial Purification during Soil Treatment of Wastewater with Multicomponent Tracer and Surrogate Tests. J. Environ. Qual. 33:316-329 (2004).   PDF file
  43. Blanford, W.J., Brusseau, M.L., Yeh, J.T.C., Gerba, C.P., Harvey, R., 2005, Bacteriophage PRD-1 transport in a sandy aquifer: Influence of water chemistry and travel distance on viability: Water Research, v. 39, p. 2345-2357.  PDF
  44. Harvey R.W. and Ryan J.N., 2004. PRD1 bacteriophage in groundwater viral transport, inactivation, and attachment studies. FEMS Microbiology Ecology 49, 3-16. PDF file
  45. Tufenkji N., Miller G.F., Ryan J.N., Harvey R.W., and Elimelech M., 2004.  Transport of Cryptosporidium oocysts in porous media: Role of straining and physicochemical filtration. Environmental Science & Technology 38, 5932-5938.  PDF file
  46. Renken R.A., Cunningham K.J., Zygnerski M.R., Wacker M.A., Shapiro A.M., Harvey R.W., Metge D.W., Osborn C.L., and Ryan J.N., 2005. Assessing the vulnerability of a municipal well field to contamination in a karst aquifer. Environmental & Engineering Geoscience 11, 319-331.  Article (pdf).
  47. Abudalo R.A., Bogatsu Y.G., Ryan J.N., Harvey R.W., Metge D.W., and Elimelech M., 2005. The effect of ferric oxyhydroxide grain coatings on the transport of bacteriophage PRD1 and Cryptosporidium parvum oocysts in saturated porous media. Environmental Science & Technology 39, 6412-6419. Article from ACS.
  48. Maxwell, RM, Welty, C, and Harvey, RW,  2007  Revisiting the Cape Cod Bacteria Injection Experiment Using a Stochastic Modeling Approach.  Environmental Science & Technology  41, 5548-5558.  PDF file
  49. Metge, DW, Harvey, RW, Anders, R, Rosenberry, DO, Seymour, D, and Jasperse, J, 2007 Use of Carboxylated Microspheres to Assess Transport Potential of Cryptosporidium parvum Oocysts at the Russian River Water Supply Facility, Sonoma County, California.  Geomicrobiology Journal 24:231–245.  PDF file
  50. Wang, M, Ford, RM, and Harvey, RW, 2008  Coupled effect of chemotaxis and growth on microbial distributions in organic-amended aquifer sediments: observations from laboratory and field studies.  PDF file
  51. Ford, RM and Harvey, RW, 2007 Role of chemotaxis in the transport of bacteria through saturated porous media.  Adv Water Resources 30:1608-1617.
    PDF file

  52. Renken, RA, KJ Cunningham, AM Shapiro, RW Harvey, MR Zygnerski, DW Metge, and MA Wacker. 2008. Pathogen and chemical transport in the karst limestone of the Biscayne aquifer: 1. Revised conceptualization of ground-water flow- In press  Water Resources Research - PDF file.
  53. Shapiro, AM, RA Renken, RW Harvey, MR Zygnerski, and DW Metge. 2008.  Pathogen and chemical transport in karst limestone of the Biscayne aquifer: 2. Chemical retention resulting from chemical diffusion and slow advection- Water Resources Research - PDF file.
  54. Harvey, RW, DW Metge, AM Shapiro, RA Renken, CL Osborn, JN Ryan, KJ Cunningham, and L Landkamer. 2008.  Pathogen and Chemical Transport in the Karst Limestone of the Biscayne Aquifer: 3. Use of microspheres to estimate the transport potential of Cryptosporidium parvum oocysts - Water Resources Research - PDF file.
  55. Gao, X, DW Metge, C Ray, RW Harvey, and J Chorover.  2009. Surface Complexation of carboxylate adheres Cryptosporidium parvum oocysts to the hematite-water interface.  Env. Sci. Technol. 43: 7423-7429.  PDF file.
  56. Abudalo RA, JN Ryan, RW Harvey, DW Metge, and L Landkamer. 2010. Influence
     of organic matter on the transport of Cryptosporidium parvum oocysts in a ferric oxyhydroxide-coated quartz sand saturated porous medium.  Water Res. 44:1104-1113.  PDF file.
  57. Harvey, RW, DW Metge, LB Barber, and GR Aiken.  2010. Effects of altered groundwater chemistry upon the pH-dependency and magnitude of bacterial attachment during transport within an organically contaminated sandy aquifer. Water Res. 44:1062-1071.  PDF file.
  58. Metge, DW, Harvey, GR Aiken, R Anders, G Lincoln and J Jasperse. 2010. Influence of organic carbon loading, sediment associated metal oxide content and sediment grain size distributions upon Cryptosporidium parvum removal during riverbank filtration operations, Sonoma County, CA.  Water Res. 44:1126-1137.  PDF file.
  59. Mohanram, A, C Ray, RW Harvey, DW Metge, JN Ryan, J Chorover, and DD Eberl.  2010.  Comparison of transport and attachment behaviors of Cryptosporidium parvum oocysts and oocyst-sized microspheres being advected through three mineralogically different granular porous media.  Water Res. 44:5334-5344.  PDF file.
  60. Harvey, RW, DW Metge, R Sheets, J Jasperse. 2010.  Fluorescent microspheres as surrogates in evaluating the efficacy of riverbank filtration for removing Cryptosporidium parvum oocysts and other pathogens. In Riverbank Filtration for Water Security in Desert Countries; Ray, C., Shamruck, M., Eds.; Amsterdam, Springer Science. p 83-98.  PDF file.
  61. Harvey, RW, DW Metge, A Mohanram, X Gao, and J Chorover.  2011.  Differential effects of dissolved organic carbon upon re-entrainment and surface properties of groundwater bacteria and bacteria-sized microspheres during transport through a contaminated, sandy aquifer.  Env. Sci. Tech.       PDF file.

  62. Underwood, JC, RW Harvey, DW Metge, DA Repert, LK Baumgartner, RL Smith, T Roane, and LB Barber.  2011.  Effects of the antimicrobial sulfamethoxazole on groundwater bacterial enrichment.  Env. Sci. Tech.       PDF file
  63. Williams, LB, DW Metge, DD Eberl, RW Harvey, AG Turner, P Prapaipong and AT Poret-Peterson. 2011. What makes a natural clay antibacterial?  Env. Sci. Tech.    High Res PDF file.   Low res PDF file
  64. Metge, DW, RW Harvey, GR Aiken, R Anders, G Lincoln, and J Jasperse. 2011. Effects of sediment-associated extractable metals, degree of sediment grain sorting, and dissolved organic carbon upon Cryptosporidium parvum removal and transport within riverbank filtration sediments, Sonoma County, California.  Env. Sci Tech.  45(13):5587-95  PDF File 

  65. Mohanram, A, C Ray, DW Metge, LBB Barber, JN Ryan, and RW Harvey.  2011. Effects of dissolved organic carbon and clay particles on the transport and attachment behaviors of Cryptosporidium parvum oocysts and carboxylate-modified microspheres advected through temperate and tropical agricultural soils.  Environ. Sci Tech. 46(14):2088-94 PDF File.

  66. Haack, SK, DW Metge, LR Fogarty, MT Meyer, LB Barber, RW Harvey, DR LeBlanc, DW Kolpin.   2012  Effects on groundwater microbial communities of an engineered 30-day in situ exposure to the antibiotic sulfamethoxazole. Environ. Sci Tech. 46(14):7478-86PDF File

  67. Bradford, SA, VL Morales, W Zhang, RW Harvey, AI Packman, A Mohanram, W Welty.  2013Critical Reviews in Environmental Science and Technology 01/2013; 43:775-893. PDF File

  68. Landkamer, LL, RW Harvey, TD Schiebe, JN Ryan 2013. Colloid transport in saturated porous media: Elimination of attachment efficiency in a new colloid transport model.  Water Res Research accepted 1/2013  PDF File


  1. Lion, L.W., Harvey, R.W., Young, L.Y., and Leckie, J.O., 1979, Particulate matter: Its association with microorganisms and trace metals in an estuarine salt marsh microlayer. Environ. Sci. Technol. Vol. 13. P. 1522-1525.
  2. Harvey, R.W. and Young, L.Y., 1980, Enrichment and association of bacteria and particulates in salt marsh surface water. Appl. Environ. Microbiol. Vol. 39, p.894-899.
  3. Harvey, R.W. and Young, L.Y., 1980, Enumeration of particle-bound and unattached respiring bacteria in the salt marsh environment. Appl. Environ. Microbiol. Vol. 40, p. 156-160.
  4. Harvey, R.W., Lion, L.W., Leckie, J.O., and Young, L.Y., 1982, Enrichment and association of lead and bacteria at particulate surfaces in a salt marsh microlayer. J. Mar. Res. Vol. 40, p. 1201-1211.
  5. Lion, L.W., Harvey, R.W., and Leckie, J.O., 1982, Mechanisms for trace metal enrichment at the surface microlayer in an estuarine salt marsh. Mar. Chem. Vol. 11, p. 235-244.
  6. Harvey, R.W., Lion, L.W., and Young, L.Y., 1983, Transport and distribution of bacteria and diatoms in the aqueous surface microlayer of a salt marsh. Estuar. Coast. Shelf Sci., Vol. 16, p. 543-547.
  7. Harvey, R.W., and Luoma, S.N., 1984, The role of bacterial exopolymer and suspended bacteria in the nutrition of the deposit-feeding clam, Macoma balthica. J. Mar. Res., Vol. 42, p. 957-968.
  8. Harvey, R.W., and Luoma, S.N., 1985, Separation of solute and particulate vectors of heavy metal uptake in controlled suspension-feeding experiments with Macoma balthica. Hydrobiologia, Vol. 121, p. 97-102.
  9. Harvey, R.W., and Luoma, S.N., 1985, Effect of adherent bacteria and bacterial extracellular polymers upon assimilation by Macoma balthica of sediment-bound Cd, Zn, and Ag. Mar. Ecol. Prog. Ser., Vol. 22, p. 281-289.
  10. Harvey, R.W., and Leckie, J.O., 1985, Sorption of lead onto two gram-negative marine bacteria in seawater. Mar. Chem., Vol. 15, P. 333-344.
  11. Harvey, R.W., 1987, A fluorochrome-staining technique for enumeration of bacteria in saline, organically enriched, alkaline lakes. Limnol. Oceanogr., Vol. 32, p. 993-995.
  12. Zehr, J.P., Harvey, R.W., Oremland, R.S., Cloern, J.C., George, L., and Lane, J.L., 1987, Big Soda Lake (Nevada). I. Pelagic bacterial heterotrophy and biomass. Limnol. Oceanogr., Vol. 32, p. 781-793.
  13. Oremland, R.S., Cloern, J.E., Smith, R.L., Culbertson, C.W., Zehr, J., Miller, L.C Cole, B., Harvey, R., Iverson, N., Klug, M., DesMarais, D.J., Rau, G., and Sofer, Z., 1988, Microbial and biochemical processes in Big Soda Lake, Nevada. In Fleet, A.J., Kelts, K., and Talbot, M.R., eds., Lacustrine Petroleum Source Rocks: Boston, Blackwell Scientific, p. 59-75.

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